Searchable abstracts of presentations at key conferences in endocrinology

ea0022p39 | Adrenal | ECE2010

The measurement of epicardial fat thickness is an index of cardiometabolic risk in patients with adrenal incidentaloma

Iorio Laura , Zelaschi Roberta , Coman Calin , Malavazos Alexis Elias , Dogliotti Giada , Corsi Massimiliano Marco , Ambrosi Bruno

An augmented cardiovascular risk is present in adrenal incidentalomas (AI), as in overt hypercortisolism. Recent studies recommended epicardial fat (EF) thickness as a new marker of visceral adiposity and an indicator of cardiometabolic risk.In this study, we evaluated the possible relationship between EF thickness, indices of left ventricular (LV) hypertrophy and adipocytokines levels in AI.We studied 26 patients with AI (62.3&#17...

ea0020p19 | Adrenal | ECE2009

Adipokine levels in patients with adrenal incidentaloma

Iorio Laura , Morelli Valentina , Coletti Francesca , Della Casa Sonia , Arosio Maura , Corsi Massimiliano , Chiodini Iacopo , Ambrosi Bruno

Patients (pts) with adrenal incidentaloma (AI) may show an increased incidence of several cardiovascular risk factors, as obesity, hypertension, diabetes mellitus and dyslipidemia. As previous data suggested that the increased cardiovascular risk in these pts could be in part mediated by alterations of adipokines, this study was aimed to evaluate plasma IL-6, resistin, CT-1 levels in a wide series of pts with AI.Ninety-three pts (42 males; 51 females; ag...

ea0022p7 | Adrenal | ECE2010

Beneficial metabolic effects of surgical treatment in patients with an adrenal incidentaloma causing subclinical hypercortisolism

Chiodini Iacopo , Morelli Valentina , Salcuni Antonio Stefano , Vainicher Cristina Eller , Torlontano Massimo , Coletti Francesca , Iorio Laura , Cuttitta Antonello , Ambrosio Angelo , Vicentini Leonardo , Pellegrini Fabio , Copetti Massimiliano , Beck-Peccoz Paolo , Arosio Maura , Ambrosi Bruno , Trischitta Vincenzo , Scillitani Alfredo

Objective: In patients with adrenal incidentalomas (AI) the metabolic effect of the recovery of subclinical hypercortisolism (SH) is debated. The aim of this study was to determine the effect of the surgical and conservative approaches on the metabolic syndrome in AI patients with and without SH.Patients: One hundred and eight AI patients were studied; SH was diagnosed in the presence of >2 out of: urinary free cortisol >70 μg/24 h (193 nmol...

ea0022p21 | Adrenal | ECE2010

Subclinical hypercortisolism: correlation between biochemical diagnostic criteria and clinical aspects

Morelli Valentina , Masserini Benedetta , Salcuni Antonio Stefano , Eller-Vainicher Cristina , Savoca Chiara , Viti Raffaella , Coletti Francesca , Guglielmi Giuseppe , Battista Claudia , Iorio Laura , Beck-Peccoz Paolo , Ambosi Bruno , Arosio Maura , Scillitani Alfredo , Chiodini Iacopo

Objective: Subclinical hypercortisolism (SH) has been associated with increased prevalence of hypertension, type 2 diabetes mellitus, dyslipidemia, central obesity, osteoporosis and vertebral fractures. We aimed to investigate the accuracy of different SH diagnostic criteria in predicting the concomitant presence of these complications.Patiets: In this retrospective study we evaluated data of 231 patients (120 females and 111 males) affected with adrenal...